Pre-conference Short Courses | Tuesday, March 18 | In-Person Only | COMING SOON!

Welcome to OPT Congress:
Oligonucleotides, mRNA & Peptide Therapeutics

OPT Congress 2026 is the leading industry event for scientists, directors, and technology providers driving innovation across oligonucleotide, mRNA, and peptide therapeutics. Now in its 11th year, this event provides a unique forum for translating cutting-edge science into transformative medicines, with expanded 2026 programming that includes the brand-new Peptides & Emerging Drug Conjugates conference. This year’s agenda brings together experts from discovery through development, with dedicated content spanning AI-enabled design, extrahepatic delivery, scalable manufacturing, and next-gen modalities including saRNA, circular RNA, and radioligand peptide conjugates.

Across four focused conferences —Oligonucleotide Discovery & Delivery, CMC & Manufacturing, mRNA & Emerging Modalities, and Peptides & Emerging Conjugates—attendees will explore 60+ scientific presentations, collaborative case studies, and real-world implementation strategies. From novel linkers and chemistries to regulatory insights, tech transfer, and delivery breakthroughs, OPT Congress fosters dialogue between pharma, biotech, academia, and technology providers. Join us for two days of actionable insights, short courses, and customizable content designed to support your therapeutic programs from bench to bedside.

 

Event Highlights and Testimonials Video
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4 Conferences
60+ Speakers
300+ Attendees
150+ Unique Organizations
Short Courses

2025 Plenary Keynote Speakers

Anastasia Khvorova, PhD

Anastasia Khvorova, PhD
Professor, RNA Therapeutic Institute, University of Massachusetts Medical School

Eric Swayze, PhD

Eric Swayze, PhD
Executive Vice President, Research, Ionis Pharmaceuticals

Edward Kaye, MD

Edward Kaye, MD
CEO and Director, Stoke Therapeutics

Ramsey Majzoub

Ramsey Majzoub, PhD
Director, Intellia Therapeutics

Our Executive Advisory Board

Marvin Caruthers, PhD
Distinguished Professor, University of Colorado

Mano Manoharan, PhD
Senior Vice President, Drug Discovery, Alnylam Pharmaceuticals

Chandra Vargeese, PhD
CTO & Head, Platform Delivery Sciences, Wave Life Sciences

Dmitry Samarsky, PhD
CSO and Board Member, GALconda Therapeutics

Arthur Levin, PhD
Board of Directors, Avidity Biosciences

Lubo Nechev, PhD
Vice President Process and Analytical Sciences, Alnylam Pharmaceuticals

Ekkehard Leberer, PhD
Senior Life Sciences Consultant, ELBIOCON